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Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2026
This article outlines the updated standards for the diagnosis and classification of diabetes as presented in the 2026 Diabetes Care guidelines. It emphasizes the importance of a...
Diabetes in Wolfram Syndrome: Recognition, Genetics, and Clinical pearls for clinicians
Wolfram syndrome is a rare, autosomal recessive neurodegenerative disorder in which early-onset insulin-dependent diabetes mellitus is a hallmark feature. Recognizing the diabet...
When diabetes is syndromic: recognizing Wolfram and related presentations in clinic
Early-onset insulin-dependent diabetes with additional neurologic, ophthalmic or urologic features should prompt evaluation for syndromic causes such as Wolfram syndrome. Recogn...
Algorithm for Recognizing and Initial Evaluation of Wolfram-related Diabetes in Clinical Practice
Consider Wolfram spectrum disorders when insulin-treated diabetes begins in childhood or adolescence and is accompanied by optic nerve dysfunction. Early structured evaluation (...
Conference Highlights: Metabolic Liver Disease, Incretins, Activity Support, and Practical Documentation in Type 2 Diabetes Care
Recent open‑access reports highlight that liver fibrosis and type 2 diabetes alter postprandial glucagon and incretin patterns, with potential implications for monitoring and th...
Practical approaches to treating diabetic neuropathy: neuroprotection, inflammation, coagulation and complementary options
Diabetic neuropathy is common, heterogeneous, and often refractory to glycemic control alone. Emerging strategies target neurotrophic support, redox and immune balance, thrombin...
Practical approach to initiating, escalating and de‑escalating insulin therapy in type 1 and type 2 diabetes
Insulin initiation should be individualized by presentation, metabolic severity, and comorbidities, with GLP‑1–based therapy preferred before insulin in many adults with type 2 ...
Practical Steps for Initiation, Escalation and De‑escalation of Insulin in Type 1 and Type 2 Diabetes
A patient-centered approach to starting, titrating, intensifying, and de‑intensifying insulin—integrating GLP‑1 receptor agonist options, basal and prandial insulin algorithms, ...
Choosing the Right Oral and Injectable Antihyperglycemic in the Indian Population: Practical, Cost‑conscious Considerations
Selection of glucose‑lowering therapy in India should balance efficacy, safety, and affordability while accounting for local delivery, storage, and disposal constraints. Practic...
Choosing a Cost-Effective Oral/Injectable Glucose-Lowering Strategy for an Indian Patient with Progressive Type 2 Diabetes
A middle-aged Indian patient with worsening hyperglycemia despite metformin requires stepwise escalation of therapy balancing effectiveness, hypoglycemia risk, and local cost/ad...